Painkillers

& Pain Management

Welcome to our painkiller and pain management section in which we summarise the most common types of pain experienced by patients, and which medicine for pain management is best at providing pain relief in each case.

Painkillers & Pain Management

If you are suffering from back pain, knee pain or shoulder pain and an online search for 'painkiller', 'buy strong painkillers' or 'pain management' has led you to our online pharmacy then you are at the right place.

  • Codeine Phosphate

    Codeine Phosphate

    Codeine Phosphate is the original brainchild of the French chemist Pierre Jean Robiquet. First discovered in the 1800s, this sensational opiate medication is considered an analgesic medication. This drug is approved to aid coughing symptoms, diarrhoea and is widely used to manage and minimize moderate pain levels. These tablets are manufactured by Ranbaxy (EU) LTD, under Sun Pharmaceuticals in the EU.

  • Dihydrocodeine

    Dihydrocodeine

    Dihydrocodeine is a strong pain killer which is used to treat moderate to severe pain. It is an opioid-based analgesic that can be used on its own or with other painkillers such as paracetamol or aspirin. It is usually used when other painkillers, including over the counter and prescription painkillers, have not been effective enough when used on their own. In the EU, it is sold under the brand name DHC Continus, and manufactured by Napp Pharmaceuticals Ltd. Napp Pharmaceuticals Ltd was founded in 1923 and it is a private pharmaceutical company based in Cambridge who produces many opioid-based medications.

  • Tramadol

    Tramadol

    Tramadol is an opioid medicine created explicitly to relieve severe pain. It is available under several brand names, including Ultram & Zydol, and can be used for both short-term and long-term pain. This means that while Tramadol is an effective treatment for acute pain, for treatment of chronic pain that lasts for over 3 months, you can continue use.

  • Pregabalin

    Pregabalin

    Pregabalin, also sold under the brand name Lyrica, belongs to the anticonvulsant class of medications. The treatment was first approved for medical use in the year 2004 and became available, being classified as a Schedule V medication. As of the year 2019, generic versions of this medication became widely available worldwide, to be used in place or expensive name-brand options.

  • Amitriptyline

    Amitriptyline

    Amitriptyline is a sedative analgesic (painkiller) and antidepressant medication used to remedy chronic depression and various pain syndromes. This painkiller has been sold under the brand name Elavil and produced by an American pharmaceutical company by the name of Merck in the 1950s. Since then, Amitriptyline has been listed as a necessary drug for use by the World Health Organization (WHO) and has been used globally with prescriptions mounting annually. You can get this dual-acting medication delivered to you right here on our website.

  • Tapentadol

    Tapentadol

    Tapentadol is one of the lesser-known painkillers that fall under the benzenoid medicine class. It is a potent opioid analgesic that functions with dual mechanisms of action, affecting the central nervous system. The treatment is available in any EU pharmacy with a prescription under several brand names, including Nucynta, Palexia, and Yantis.

  • Carisoprodol

    Carisoprodol

    Carisoprodol is a medication used as a muscle relaxant for the treatment of muscular and skeletal pain. Due to its ability to target the GABA receptors, it is also used for off label treatment for insomnia and anxiety. It is sold under the brand name Soma, manufactured by the pharmaceutical company Oxford Pharma and was approved medically for generic use in 1959. Generic medications have seen a steady increase in use due to their reliability and consistency.

  • Co-codamol

    Co-codamol

    Co-codamol is a compound medication containing opioid-based codeine-phosphate and acetaminophen (paracetamol). This generic version of branded versions, including Kapake, Solpadol and Tylex, is produced by Zentiva Pharma EU limited in the United Kingdom and licensed as a short-term treatment solution for mild to moderate kinds of pain. The types of conditions this medication typically treats include migraines, toothaches and muscular or back pain.

What Are Painkillers?

Painkillers, also known as analgesics, are medicines used to relieve pain. They work in a number of different ways depending on the type of painkiller, and the right choice depends on the type, severity and cause of the pain being treated.

How Do Painkillers Work?

Most painkillers work by blocking pain signals travelling from the site of an injury to the brain, or by interfering with the brain's interpretation of those signals. Others reduce inflammation, which in turn lowers the amount of pain being generated. Different categories of pain relief include:

  • Combination analgesics such as co-codamol combine paracetamol with codeine for stronger relief than either alone.
  • Opioid painkillers such as codeine, dihydrocodeine and tramadol act on the central nervous system to reduce the perception of pain.
  • Nerve pain treatments such as pregabalin and amitriptyline are used for neuropathic pain, including nerve-related back pain and migraine.
  • Muscle relaxants such as carisoprodol help to relieve pain caused by muscle spasms and injury.

Which Painkiller Is Right for Me?

The best painkiller depends on the type of pain you are experiencing. Mild to moderate pain is often treated with simple analgesics, while moderate to severe pain may require a stronger opioid-based medication such as tapentadol. For nerve pain, medicines such as pregabalin and amitriptyline are usually more effective than ordinary painkillers.

Painkiller Safety and Side Effects

All painkillers can cause side effects, and it is important to follow the dosage instructions in the patient information leaflet carefully. Common side effects include drowsiness, dizziness, nausea and constipation, particularly with opioid-based products.

You should never mix painkillers with alcohol, and you should always check with a doctor or pharmacist before combining different painkillers. If you experience any unusual side effects, seek medical advice as soon as possible.

What are Painkillers?

When it comes to pain management, there are three main options: non-steroidal anti-inflammatory drugs (NSAIDS), paracetamol and opioids. Because there are different types of pain and different causes, each of these three types work in different ways.

Most pain does not last long and sufferers do not need to take painkillers for more than a few days or weeks at most. However, in some cases people need to take them for extended periods.

While many NSAID painkillers such as ibuprofen, or general pain relief pills like paracetamol are available over the counter at most high street chemists. Opioid painkillers as codeine or tramadol are strong painkillers, and usually prescribed for acute and chronic pain management.

Acute pain occurs abruptly and the cause is often specific. It. Acute pain is usually described a sharp or stabbing, but does not last longer than six months and ends when the original cause has been successfully treated.
Causes of acute pain include:

  • Surgery
  • Broken bones
  • Dental work
  • Burns or cuts

Chronic pain is constant and generally lasts longer than six months. People who suffer from chronic pain sometimes develop physical effects that become stressful on the body. These include tense muscles, limited ability to move around, a lack of energy, and appetite changes.

This type of pain can also cause mental problems that include depression, anger, anxiety, and fear of re-injury.

Some causes of chronic pain are:

  • Headache
  • Arthritis
  • Cancer
  • Nerve pain
  • Back pain
  • Fibromyalgia pain

Because the causes of acute pain are easier to diagnose the pain is also much easier to treat, but some people have been known to suffer chronic pain even when there is no history of injury or noticeable damage to the body.

A recent study estimated that a staggering 43% of adults are experiencing some form of chronic pain. As worrying as these studies results are, it is perhaps more concerning to think that many of these sufferers, particularly those with nerve and back pain, are struggling on in silence and their pain is not receiving effective treatment.

HOW TO PAINKILLERS WORK?

How people feel pain is a complicated issue and is a combination of not only the nerves in your body and brain, but also our emotions. Each individual experiences pain in a personal and unique way, and even our surroundings and mood can affect how much pain is felt.

Added to this complexity each of the three different kinds of painkiller work in a different way, so experts often recommend that we should start to treat pain with the mildest medication and increase the strength if the pain persists.

Despite having a long history dating back to the 19th Century and being used in almost every home in the world , we are still not exactly sure how paracetamol works. Scientists believe that it works mainly in the bodies central nervous system (the brain and the spine).

It is thought to decrease the strength and number of pain signals going to the brain, it may also work in a similar way to NSAIDs by blocking the release of a hormone called prostaglandins.

Non-steroidal anti-inflammatory works by blocking special hormones called prostaglandins. The body uses these hormones as part of the healing process, but part of that process causes pain and swelling.

Although opioids are the strongest group of painkillers, they can be separated into two smaller groups of weaker (codeine and dihydrocodeine) and stronger (tramadol). These analgesic medications work by triggering opioid receptors on nerve cells.

These receptors are part of a family of proteins known as G protein-coupled receptors (GPCRs) and block the brain's sensation of pain.

Because painkillers work in different ways, there are some products available that contain more than one type of painkiller. For example, co-codamol is a combination of paracetamol and codeine.

Opioids have been used for thousands of years for the treatment of pain, and are the most widely used and effective analgesics for the treatment of pain and related disorders.

If you are taking several painkillers, read the patient information leaflets to make sure you do not accidentally take too much, or if you are still unsure ask a pharmacist for advice.

PAIN MANAGEMENT

Dealing with any amount of pain can bring a person's day to a grinding halt. This makes it important to prepare yourself by ordering painkillers that are sure to leave you free from your form of physical discomfort.

The wide variety of medicines used to relieve people of their pains can be overwhelming to try and decipher for yourself, but very few have the painkilling power needed to provide you with the results that you have been in search of to get the swiftest possible relief.

The most sought-after medications that licensed medical professionals commonly recommend would include generic variants of codeine, pregabalin, dihydrocodeine, tramadol and co-codamol.

These treatments are regularly prescribed to patients who are in pain as they are widely renowned for being some of the most powerful pain killers currently available on the global market.

While medications as powerful as the ones mentioned above are often sold at exorbitant prices, their generic alternatives help you side step these prices while still providing you with an effective and unmatched sense of relief from the pain that has been inhibiting you from living a happy life.

WHICH PAINKILLER IS BEST

It is important to understand how each medication works to determine which painkiller is best suited for your condition.

To treat mild discomfort that is caused by muscle tension and headaches, co-codamol tablets may be your best bet. These tablets are made up of two separate active components. These ingredients include 30 mg of codeine phosphate paired with 500 mg of paracetamol within each tablet.

Another effective pain remedy includes pregabalin, which allows its users to get swift relief from nerve pain. Specifically, pregabalin helps its users overcome the pain that may be caused by diabetic neuropathy, post-herpetic neuralgia, as well any discomfort caused by a spinal cord injury. When combined with other medicines, pregabalin can aid those who suffer from partial onset seizures too.

If you are looking for a medication that is able to keep you free of moderate to severe pain around the clock, then tramadol may prove most useful to you. When taken at regular intervals, tramadol is able to provide you with a constant sense of relief from your discomfort that is guaranteed to take effect within an hour of taking your first dosage.

Then there is codeine, an opioid painkiller that is able to treat much more than just your average headache. While still incredibly useful against other mild instances of pain, codeine can also be used by those seeking relief from coughing and diarrhoea too.

BUY PAINKILLERS ONLINE

For people looking for a reliable pharmacy and a fast home delivery service from which you can buy strong pain medication online without a prescription then you are at the right place.

Although many pain relief remedies are available in high street pharmacies, it can be incredibly difficult to find a chronic pain treatment that is both effective as well as affordable.

By choosing to buy strong painkillers from our online pharmacy, you can expect to have your pain and discomfort cleared up completely in no time at all while still enjoying the benefits of a discreet doorstep delivery service.

We also stock a wide range of sleeping pills along with several anxiety medication options.

If you have any questions regarding insomnia treatment or the products sold on our website our friendly customer service staff are available to assist 24/7 via phone, live chat and email.

ABOUT PAINKILLERS / PAIN MEDICATION

ARE THERE DIFFERENT TYPES OF PAINKILLERS?

Yes, there are different types of Painkillers that treat a multitude of conditions. Based on the level of pain that you experience painkillers vary from mild painkillers (paracetamol and aspirin) to painkillers that treat moderate to severe pain (Codeine and Tramadol).

WHAT IS THE STRONGEST PAINKILLER?

Tramadol is widely regarded as the strongest pain killer available on the market. Treating moderate to severe pain Tramadol directly targets the pain receptors in the brain and central nervous system providing relief from the severest of pain.

WHICH PAINKILLER IS BEST?

The best painkillers are what your Doctor recommends to treat your condition. There is no substitute for professional medical advice and both the type of medication and dosage instructions should be followed closely for the best results.

IS CODEINE STRONGER THAN TRAMADOL?

Codeine and Tramadol belong to the Opioid analgesic family of medicines and are both regarded as strong painkillers. It is however recognised that Tramadol is the stronger medication.

WHAT PAINKILLERS CAN I BUY ONLINE?

A wide variety of painkillers are available online including Codeine, Tramadol, Pregabalin & Carisoprodol. Established online pharmacies also offer safe and secure payment options, quick and discreet delivery as well as around the clock customer service.

Last Reviewed: 13th November 2025
Next Review Due: December 2026

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